PA-OTP 11: Dosage Requirements
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Opioid treatment medication is administered as follows:
- a physician makes all dosage decisions within the medically accepted dosage range for effective treatment;
- conditions for use are documented in the person’s case record;
- medications are administered and dispensed in accordance with approved product labeling;
- the initial dose of methadone does not exceed 30 milligrams, and 40 milligrams as a total dose for the first day; and
- methadone is dispensed in oral form.
Interpretation: The physician may exceed the 40 milligrams total dose if it is determined that the previous dosage did not suppress the person’s withdrawal symptoms.
Interpretation: The initial dose of methadone must be determined by an OTP physician familiar with the most up-to-date product labeling, who considers factors, such as body weight, size, other substance-use and abuse, diet, co-occurring disorders, medical diseases, genetic factors, and tolerance. Although the initial dose is indicated not to exceed 30 milligrams, this dose is not appropriate for everyone, and some individuals may require much lower doses. All individuals should be closely monitored during the induction phase and the increases in dosage should be under the close
supervision of the physician. It must be documented in the case record when the 40 milligrams total dose is exceeded based on the physician’s determination that the previous dosage did not suppress the person’s withdrawal symptoms.
When a physician determines a person is eligible to receive take-home medication, the dose is limited to no more than:
- one dose per week in the first 90 days of treatment;
- two doses per week in the second 90 days of treatment;
- three doses per week in the third 90 days of treatment;
- a six-day supply in the remaining months of the year;
- a two-week supply after one year of continuous treatment; and
- a one-month supply after two years of continuous treatment.
Service recipients receive the appropriate dosage of opioid treatment medication for days when the clinic is closed, for weekends, holidays, and travel.
Interpretation: The agency informs individuals of its plan for administration of medication in the event that the program is temporarily closed due to an emergency.